Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792259 | 0.91 | MEN1 (0.43) | MAPTMEN1KMT2ALMNARECQL | |
| SCHEMBL7792628 | 0.89 | SPHK2 (0.48) | KMT2ALMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL7792325 | 0.82 | GRIN1 (0.44) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7792625 | 0.81 | SPHK2 (0.48) | KMT2ALMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL7792323 | 0.79 | PIN1 (0.61) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL7794740 | 0.77 | HRH4 (0.52) | MAPTKMT2AEGFRPOLBALDH1A1 | |
| SCHEMBL7796362 | 0.76 | EGLN1 (0.57) | MAPTMEN1KMT2ALMNAFPR2 | |
| Hydrochloric Acid SCHEMBL7794721 | 0.76 | HRH4 (0.51) | MAPTKMT2AEGFRALDH1A1HPGD | |
| SCHEMBL7795897 | 0.75 | MEN1 (0.50) | MAPTMEN1KMT2ALMNARECQL | |
| SCHEMBL7795735 | 0.75 | PKN1 (0.55) | MAPTMEN1KMT2APOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |