SCHEMBL7792259

SCHEMBL7792259

CCC(=O)Nc1ccc2[nH]c(C(=O)SCCCCCSC(=O)c3nc4cc(NC(=O)CC)ccc4[nH]3)nc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 3/20 0.41
LMNA P02545 6/20 0.39
RECQL P46063 1/20 0.39
PDE10A Q9Y233 1/20 0.39
CYP3A4 P08684 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
RAB9A P51151 5/20 0.38
NPC1 O15118 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
RORC P51449 1/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792262 0.91 MAPT (0.46) MEN1KMT2APOLBMAPTLMNA
SCHEMBL7792625 0.89 SPHK2 (0.48) KMT2APOLBLMNARAB9ANPC1
SCHEMBL7792322 0.82 MMP2 (0.42) SMN1; SMN2HDAC6
SCHEMBL7792628 0.81 SPHK2 (0.48) KMT2APOLBLMNARAB9ANPC1
SCHEMBL7792319 0.79 PIN1 (0.47) MEN1KMT2APOLBMAPTLMNA
SCHEMBL7795870 0.79 BRD4 (0.42) MEN1KMT2ALMNAHPGDKDM4E
SCHEMBL7794739 0.77 HRH4 (0.41) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL7796360 0.76 EGLN1 (0.46) MEN1KMT2APOLBMAPTLMNA
Hydrochloric Acid SCHEMBL7794719 0.76 HRH4 (0.40) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL7795890 0.75 MEN1 (0.49) MEN1KMT2APOLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742210-B1 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME FUJI PHOTO FILM CO LTD (JP) 2001-11-21 EP disclosed
US-5962493-A HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1999-10-05 US disclosed
EP-0742210-A1 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1996-11-13 EP disclosed