Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.42 |
| ▸ | LTA4H | P09960 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL7792582 | 1.00 | ENPP2 (0.42) | ENPP2LTA4HALDH1A1MAPTHPGD | |
| Lysine SCHEMBL7800240 | 0.98 | ENPP2 (0.42) | ENPP2LTA4HALDH1A1MAPTHPGD | |
| Lysine SCHEMBL7800242 | 0.98 | ENPP2 (0.42) | ENPP2LTA4HALDH1A1MAPTHPGD | |
| Ornithine Aketoglutarate SCHEMBL7802652 | 0.93 | ENPP2 (0.42) | ENPP2LTA4H | |
| Ornithine SCHEMBL7802654 | 0.93 | ENPP2 (0.42) | ENPP2LTA4H | |
| Ornithine SCHEMBL7798220 | 0.93 | ENPP2 (0.46) | ENPP2LTA4HALDH1A1MAPTHPGD | |
| Ornithine Aketoglutarate SCHEMBL7798218 | 0.93 | ENPP2 (0.46) | ENPP2LTA4HALDH1A1MAPTHPGD | |
| 2-Naphthylacetic Acid SCHEMBL7798213 | 0.92 | NR1H4 (0.43) | ENPP2LTA4HSLC1A3SLC1A2SLC1A1 | |
| 2-Naphthylacetic Acid SCHEMBL7798211 | 0.92 | NR1H4 (0.43) | ENPP2LTA4HSLC1A3SLC1A2SLC1A1 | |
| Ornithine SCHEMBL7800254 | 0.92 | ENPP2 (0.44) | ENPP2LTA4HALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |