Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine SCHEMBL7802654 | 1.00 | ENPP2 (0.42) | ENPP2KMT2AMEN1NPC1RAB9A | |
| Lysine SCHEMBL7801579 | 0.98 | ENPP2 (0.42) | ENPP2KMT2AMEN1NPC1RAB9A | |
| Lysine SCHEMBL7801581 | 0.98 | ENPP2 (0.42) | ENPP2KMT2AMEN1NPC1RAB9A | |
| Phenylacetic Acid SCHEMBL7792582 | 0.93 | ENPP2 (0.42) | ENPP2LTA4H | |
| Phenylacetic Acid SCHEMBL7792579 | 0.93 | ENPP2 (0.42) | ENPP2LTA4H | |
| Ornithine SCHEMBL7800424 | 0.91 | MEN1 (0.42) | KMT2AMEN1SMN1; SMN2LTA4HIDO1 | |
| Ornithine Aketoglutarate SCHEMBL7801606 | 0.91 | ENPP2 (0.41) | ENPP2SMN1; SMN2LTA4H | |
| Ornithine SCHEMBL7801608 | 0.91 | ENPP2 (0.41) | ENPP2SMN1; SMN2LTA4H | |
| Lysine SCHEMBL7800240 | 0.91 | ENPP2 (0.42) | ENPP2LTA4H | |
| Lysine SCHEMBL7800242 | 0.91 | ENPP2 (0.42) | ENPP2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |