SCHEMBL7792780

SCHEMBL7792780

NCCCCC1=C(Cl)C(=O)c2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
DNMT1 P26358 1/20 0.50
DNMT3L Q9UJW3 1/20 0.50
DNMT3A Q9Y6K1 1/20 0.50
MAPT P10636 6/20 0.41
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 3/20 0.41
NPSR1 Q6W5P4 3/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
MAOA P21397 1/20 0.41
TDP1 Q9NUW8 9/20 0.40
HTT P42858 4/20 0.40
LMNA P02545 4/20 0.40
MITF O75030 2/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
NSD2 O96028 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9627850 0.83 PTPN1 (0.51) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL9627508 0.81 PTPN1 (0.54) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL10956573 0.81 PTPN1 (0.54) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL10954496 0.81 PTPN1 (0.54) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL10953110 0.81 IDO1 (0.52) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL31414637 0.78 MAPT (0.46) MAPTALDH1A1RAB9ANPSR1CASP3
SCHEMBL9628338 0.77 MAPT (0.56) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL11415987 0.77 IDO1 (0.56) IDO1DNMT1DNMT3LDNMT3AMAPT
SCHEMBL4453652 0.74 MAPT (0.49) IDO1MAPTALDH1A1RAB9ATDP1
SCHEMBL9627696 0.72 IDO1 (0.60) IDO1DNMT1DNMT3LDNMT3AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584794-B1 Electrobiochemical analytical method and electrodes YISSUM RES DEV CO (IL) 2001-12-05 EP disclosed
US-5443701-A Electrobiochemical analytical method and electrodes YISSUM RESEARCH DEVELOPMENT COMPANY OF HEBREW UNIVERSITY OF JERUSALEM (IL) 1995-08-22 US disclosed
EP-0584794-A2 Electrobiochemical analytical method and electrodes YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1994-03-02 EP disclosed