Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627850 | 0.95 | PTPN1 (0.51) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL10954496 | 0.93 | PTPN1 (0.54) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL10956573 | 0.93 | PTPN1 (0.54) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL9627508 | 0.93 | PTPN1 (0.54) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL9628338 | 0.89 | MAPT (0.56) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL9627696 | 0.81 | IDO1 (0.60) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL7792780 | 0.81 | IDO1 (0.50) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL31611869 | 0.80 | PTPN1 (0.46) | MAPTALDH1A1MITFPTPN1NPSR1 | |
| SCHEMBL571120 | 0.80 | PKM (0.54) | IDO1MAPTALDH1A1LMNATDP1 | |
| SCHEMBL28562369 | 0.79 | PTPN1 (0.45) | MAPTALDH1A1MITFPTPN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172076-A1 | NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-11-12 | — | — | WO | disclosed |
| US-4507241-A | Method for the hydrocarbylation of naphthoquinone derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-26 | — | — | US | disclosed |