SCHEMBL7792880

SCHEMBL7792880

Cc1cc(C(C)(C)C)cc(CC(=O)O)c1O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RXRB P28702 4/20 0.56
RXRA P19793 3/20 0.56
NR1H4 Q96RI1 5/20 0.47
CYP2C19 P33261 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47
RXRG P48443 2/20 0.46
ALDH1A1 P00352 1/20 0.42
CD69 Q07108 2/20 0.40
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
HIF1A Q16665 1/20 0.39
ALOX15 P16050 1/20 0.39
ELANE P08246 1/20 0.38
AGBL2 Q5U5Z8 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27678601 0.92 RXRB (0.50) RXRBRXRANR1H4CYP2C19CYP1A2
SCHEMBL5605119 0.84 RXRA (0.48) RXRBRXRANR1H4CYP2C19CYP1A2
SCHEMBL5608318 0.83 NPSR1 (0.55) RXRBRXRANR1H4CYP2C19CYP1A2
SCHEMBL31603748 0.81 CYP2C19 (0.51) RXRBRXRACYP2C19CYP1A2CYP2D6
SCHEMBL10046766 0.81 CYP2C19 (0.51) RXRBRXRACYP2C19CYP1A2CYP2D6
SCHEMBL18050561 0.80 MAPT (0.43) RXRBRXRACYP2C19CYP1A2CYP2D6
SCHEMBL18050492 0.79 CYP2C19 (0.42) RXRBRXRACYP2C19CYP1A2CYP2D6
SCHEMBL70807 0.79 CYP2C19 (0.53) CYP2C19CYP1A2CYP2D6CYP2C9ALDH1A1
SCHEMBL11599008 0.79 RXRA (0.56) RXRBRXRANR1H4CYP2C19CYP2D6
SCHEMBL7796088 0.78 RXRA (0.52) RXRBRXRANR1H4RXRGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105087110-B Lubricant oil composite 吉坤日矿日石能源株式会社 2018-04-27 CN disclosed
CN-105087111-B Lubricant oil composite 吉坤日矿日石能源株式会社 2018-03-13 CN disclosed
CN-105087111-A Lubricant composition JX NIPPON OIL & ENERGY CORP 2015-11-25 CN disclosed
CN-105087110-A Lubricating oil composition JX NIPPON OIL & ENERGY CORP 2015-11-25 CN disclosed
CN-105087112-A Lubricating oil composition JX NIPPON OIL & ENERGY CORP 2015-11-25 CN disclosed
CN-105018189-A Lubricating oil compound JX NIPPON OIL & ENERGY CORP 2015-11-04 CN disclosed
CN-101688146-B Lubricating oil composition for shock absorber IDEMITSU PETROCHEMICAL CO 2013-03-27 CN disclosed
CN-101688146-A Lubricating oil composition for shock absorber IDEMITSU PETROCHEMICAL CO 2010-03-31 CN disclosed
CN-1938408-A Lubricating composition for industrial machinery NIPPON OIL CORP (JP) 2007-03-28 CN disclosed
CN-1213133-C Lubricating oil composition for papermaking machine NIPPON MITSUBISHI OIL CORP (JP) 2005-08-03 CN disclosed
CN-1346872-A Lubricating oil composition for papermaking machine NIPPON MITSUBISHI OIL CORP (JP) 2002-05-01 CN disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed