Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.56 |
| ▸ | RXRB | P28702 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.54 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580573 | 0.87 | RXRA (0.71) | RXRARXRBNR1H4RXRGCYP2C19 | |
| SCHEMBL20575945 | 0.84 | RXRA (0.57) | RXRARXRBNR1H4RXRG | |
| SCHEMBL30120956 | 0.84 | RXRA (0.57) | RXRARXRBNR1H4RXRG | |
| SCHEMBL7795903 | 0.84 | CYP2D6 (0.59) | RXRARXRBNR1H4RXRGCYP2C19 | |
| SCHEMBL13580640 | 0.83 | NR1H4 (0.59) | RXRARXRBNR1H4RXRGLMNA | |
| SCHEMBL3567193 | 0.81 | TDP1 (0.51) | RXRARXRBNR1H4RXRGCYP2C19 | |
| SCHEMBL14076377 | 0.80 | RXRA (0.54) | RXRARXRBNR1H4RXRGCYP2C19 | |
| SCHEMBL29335336 | 0.79 | KIF11 (0.47) | LMNACYP2C19EPHX2CYP2D6 | |
| SCHEMBL7792880 | 0.79 | RXRB (0.56) | RXRARXRBNR1H4RXRGCYP2C19 | |
| SCHEMBL8038901 | 0.79 | CYP2D6 (0.41) | RXRARXRBNR1H4LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069271-A | ISOMERIZATION, DEHYDROGENATION, OXIDATION, REDUCTION, TRANSITION METAL | STANDARD OIL COMPANY (INDIANA) (US) | 1978-01-17 | — | — | US | disclosed |
| US-4005049-A | FOR ISOMERIZATION, DEHYDROGENATION, REDUCTION AND MILD OXIDATION | STANDARD OIL COMPANY (INDIANA) (US) | 1977-01-25 | — | — | US | disclosed |