Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345613 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAOBPARP15PARP10PARP14 | |
| SCHEMBL7793842 | 0.85 | IDO1 (0.43) | MAOBIDO1DPP4DPP7 | |
| SCHEMBL7792911 | 0.81 | SLC1A3 (0.51) | ALDH1A1PARP10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7789772 | 0.78 | MAOB (0.40) | ALDH1A1MAOBPARP10IDO1DPP4 | |
| SCHEMBL7792922 | 0.77 | MAOB (0.45) | MAOBPARP10IDO1SCN9A | |
| SCHEMBL7792899 | 0.75 | ALDH1A1 (0.62) | ALDH1A1MAOBPARP15PARP10PARP14 | |
| SCHEMBL7347112 | 0.73 | PARP10 (0.40) | ALDH1A1MAOBPARP10NPC1LMNA | |
| SCHEMBL7794363 | 0.72 | MAOB (0.43) | ALDH1A1MAOBSLC1A5LMNAMAPT | |
| SCHEMBL4800096 | 0.69 | ALDH1A1 (0.46) | ALDH1A1MAOBPARP15PARP10PARP14 | |
| SCHEMBL4798690 | 0.68 | ALDH1A1 (0.49) | ALDH1A1MAOBPARP15PARP10PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044547-A1 | Antiviral protease inhibitors | MEDIVIR AB | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044547-A1 | Antiviral protease inhibitors | PEPD, PREP, CTSL | ALDH1A1 1578/4885MAOB 1597/4885PARP15 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.