SCHEMBL7792934

SCHEMBL7792934

CCCCOC(=O)C(C)(N)C#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 6/20 0.43
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.41
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
LMNA P02545 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
PDE4D Q08499 1/20 0.37
NAAA Q02083 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28243676 1.00 ALDH1A1 (0.44) ALDH1A1TSHRHPGDATMMAPT
SCHEMBL18704240 0.81 ALDH1A1 (0.47) ALDH1A1TSHRHPGDATMHCAR2
SCHEMBL28242894 0.81 MEN1 (0.53) ALDH1A1TSHRHPGDMAPTLMNA
SCHEMBL28242892 0.81 MEN1 (0.53) ALDH1A1TSHRHPGDMAPTLMNA
SCHEMBL27869320 0.79 ALDH1A1 (0.52) ALDH1A1TSHRHPGDATMMAPT
SCHEMBL3412121 0.79 ALDH1A1 (0.52) ALDH1A1TSHRHPGDATMMAPT
SCHEMBL862703 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHPGDATMHCAR2
SCHEMBL8397276 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHPGDATMHCAR2
Hydrochloric Acid SCHEMBL18492368 0.77 ALDH1A1 (0.50) ALDH1A1TSHRHPGDATMMAPT
SCHEMBL9286243 0.77 ALDH1A1 (0.50) ALDH1A1TSHRHPGDATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108586488-B Photocatalytic synthesis method of Diels-Alder adduct as intermediate of vitamin B6 浙江新和成股份有限公司 2020-05-12 CN disclosed
CN-108586488-A A kind of photocatalytic synthesis method of vitamin B6 intermediate Diels-Alder addition products 浙江新和成股份有限公司 2018-09-28 CN disclosed
EP-1157004-A1 REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES IDEC PHARMACEUTICALS CORPORATION (US) 2001-11-28 EP disclosed
WO-2000051976-A1 REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES IDEC PHARMACEUTICALS CORPORATION (US) 2000-09-08 WO disclosed