Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626937 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL8399191 | 0.81 | MEN1 (0.48) | ALDH1A1TSHRLMNA | |
| SCHEMBL8397278 | 0.79 | MEN1 (0.34) | ALDH1A1TSHRHPGDATML3MBTL1 | |
| SCHEMBL7792934 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL28243676 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL18704240 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL28432881 | 0.78 | MEN1 (0.44) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL28897274 | 0.77 | MEN1 (0.43) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL862703 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL31432928 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932747-A | Method for preparing 1,3-dioxane compounds | HUELS AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | claimed |
| US-5932747-A | Method for preparing 1,3-dioxane compounds | HUELS AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |