Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7793210

COc1ccc2c(c1)c(C(=O)Oc1c(F)ccc(F)c1F)c1cc(OC)ccc1[n+]2C.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.37
KCNH2 Q12809 2/20 0.36
PPM1A P35813 1/20 0.32
HSP90AA1 P07900 1/20 0.32
G6PD P11413 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL7796548 0.95 KCNH2 (0.35) ACHEKCNH2HSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL7793794 0.90 KCNH2 (0.35) ACHEKCNH2HSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL38661828 0.85 KCNH2 (0.36) ACHEKCNH2PPM1AHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL6587832 0.84 ACHE (0.35) ACHEKCNH2
Trifluoromethanesulfonic Acid SCHEMBL38662584 0.83 KCNH2 (0.34) ACHEKCNH2PPM1AHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL38661531 0.82 KCNH2 (0.39) ACHEKCNH2
Trifluoromethanesulfonic Acid SCHEMBL7795306 0.82 KCNH2 (0.38) ACHEKCNH2HSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL38663367 0.82 KCNH2 (0.38) ACHEKCNH2HSP90AA1G6PD
SCHEMBL6588162 0.79 ACHE (0.39) ACHE
Trifluoromethanesulfonic Acid SCHEMBL7703955 0.79 ABHD6 (0.40) ACHEKCNH2PPM1AHSP90AA1G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750748-B1 NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 2001-12-05 EP disclosed
US-5750698-A USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE LUMIGEN, INC. (US) 1998-05-12 US disclosed
US-5593845-A BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY LUMIGEN, INC. (US) 1997-01-14 US disclosed