Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797022 | 0.93 | HDAC4 (0.49) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7755171 | 0.85 | SNCA (0.42) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7793833 | 0.84 | HDAC4 (0.49) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7787061 | 0.77 | MAPT (0.37) | ALDH1A1MAPTSMN1; SMN2HSD17B10PTGDR2 | |
| SCHEMBL38665317 | 0.77 | ALDH1A1 (0.39) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL38664719 | 0.77 | ATM (0.40) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7787073 | 0.75 | ALDH1A1 (0.38) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7592240 | 0.75 | MAPT (0.41) | ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL8741716 | 0.74 | SMN1; SMN2 (0.39) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL38664476 | 0.74 | LPAR1 (0.41) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | claimed |