Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793833 | 0.85 | HDAC4 (0.49) | MAPTKDM4EALDH1A1HDAC4HDAC7 | |
| SCHEMBL7592395 | 0.79 | TAS1R3 (0.34) | MAPTMAPK1POLBMEN1KMT2A | |
| SCHEMBL7797022 | 0.77 | HDAC4 (0.49) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL8331335 | 0.76 | MAPT (0.41) | MAPTKDM4EALDH1A1POLBHDAC4 | |
| SCHEMBL7031997 | 0.76 | HDAC4 (0.45) | MAPTKDM4EALDH1A1HDAC4HDAC7 | |
| SCHEMBL8332928 | 0.76 | HDAC4 (0.45) | MAPTKDM4EALDH1A1MAPK1POLB | |
| SCHEMBL7793219 | 0.75 | LMNA (0.43) | MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7755161 | 0.75 | HDAC4 (0.42) | ALDH1A1HDAC4HDAC7HDAC5SLC6A2 | |
| SCHEMBL8331202 | 0.75 | CA12 (0.39) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7587330 | 0.74 | BRD4 (0.33) | MAPTPOLBAKR1C3AKR1C2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778946-B1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN INC (US) | 2002-10-23 | — | — | EP | claimed |