Cyclopropane

Cyclopropane

SCHEMBL7793245

C1CC1.CCC(CC)C(=O)OCCOC(=O)C(CC)CC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
TSHR P16473 2/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 2/20 0.34
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579645 1.00 ALDH1A1 (0.40) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL416753 0.92 CA2 (0.43) ALDH1A1CA2CA1HDAC3HDAC4
Ethylene SCHEMBL1732619 0.87 CA2 (0.40) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL415008 0.85 ALDH1A1 (0.44) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL79010 0.85 ALDH1A1 (0.44) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL11139903 0.85 ALDH1A1 (0.44) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL80272 0.85 ALDH1A1 (0.44) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL11286569 0.83 CA1 (0.38) ALDH1A1CA2CA1HDAC3HDAC4
SCHEMBL415923 0.82 CA2 (0.45) ALDH1A1CA2CA1TSHRMAPK1
SCHEMBL415575 0.82 CA2 (0.45) ALDH1A1CA2CA1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0631861-B1 Plasticized polyvinyl butyral sheet containing epoxy resin SOLUTIA INC (US) 2001-12-19 EP disclosed
US-5631315-A IMPROVED ADHESION TO GLASS SHEETS WITH METAL OXIDE REFLECTIVE COATINGS AND/OR ELECTRICALLY CONDUCTIVE COATINGS MONSANTO COMPANY (US) 1997-05-20 US disclosed
US-5529848-A LIGHT TRANSMITTING SAFETY GLAZINGS FOR WINDOWS, WINDSHIELDS, SUNROOF, SKYLIGHTS; ADHESION STABILITY MONSANTO COMPANY (US) 1996-06-25 US disclosed
US-5529849-A LAMINATED GLAZING PANELS WITH STABILIZED ADHESION TO PHOTOREACTIVE LAYERS(RADIATION-REFLECTING OR ELECTROCONDUCTIVE COATINGS) MONSANTO COMPANY (US) 1996-06-25 US disclosed
EP-0631861-A1 Plasticized polyvinyl butyral sheet containing epoxy resin MONSANTO COMPANY (US) 1995-01-04 EP disclosed