Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793321 | 1.00 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL2608307 | 0.88 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL11743247 | 0.88 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL11742077 | 0.88 | GRIN2D (0.64) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL12010979 | 0.88 | GRIN2D (0.64) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7793225 | 0.83 | NFE2L2 (0.56) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL7793229 | 0.83 | NFE2L2 (0.56) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL10024994 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL28883389 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE | |
| SCHEMBL22366969 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2NFE2L2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |