Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485887 | 0.91 | HRH4 (0.44) | ALDH1A1TRPV1HRH4HRH3MEN1 | |
| SCHEMBL22542050 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRPOLBCNR1CNR2 | |
| SCHEMBL4168246 | 0.82 | MEN1 (0.43) | ALDH1A1TRPV1HRH4HRH3MEN1 | |
| SCHEMBL6872363 | 0.82 | TYR (0.44) | ALDH1A1TRPV1S1PR1HRH4HRH3 | |
| SCHEMBL6608762 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRTRPV1HRH4HRH3 | |
| SCHEMBL15013072 | 0.82 | TRPA1 (0.49) | ALDH1A1TRPV1HRH4HRH3GAA | |
| SCHEMBL516360 | 0.81 | MEN1 (0.49) | ALDH1A1TSHRPOLBNPC1RAB9A | |
| SCHEMBL20733110 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRNPC1RAB9ATRPM8 | |
| SCHEMBL19227318 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRNPC1RAB9ATRPM8 | |
| SCHEMBL20733138 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRNPC1RAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350180-A | Industrial preparation method and application of high-purity alpha-aminonitrile | 哈尔滨理工大学 | 2025-01-24 | — | — | CN | claimed |
| EP-0676429-B1 | Composition for urethane-based plastic lens | MITSUI CHEMICALS INC (JP) | 2000-12-27 | — | — | EP | claimed |
| CN-119350180-A | Industrial preparation method and application of high-purity alpha-aminonitrile | 哈尔滨理工大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-105189132-B | Thermosensitive recording medium exhibiting gold metallic tone and/or thermosensitive recording medium exhibiting two different tones | 王子控股株式会社 | 2018-06-26 | — | — | CN | disclosed |
| CN-101679596-B | Super-high refractive index optical resin composition having high heat deflection temperature and excellent thermal stability, optical lens using same and method for manufacturing the optical lens | KOC SOLUTION CO LTD | 2013-02-20 | — | — | CN | disclosed |
| US-8258129-B2 | 4-heterocycloalkylpyri(mi)dines, process for the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-09-04 | — | — | US | disclosed |
| CN-101679596-A | Super-high refractive index optical resin composition having high heat deflection temperature and excellent thermal stability, optical lens using same and method for manufacturing the optical lens | SHIN DAE SPECIALTIES CO LTD | 2010-03-24 | — | — | CN | disclosed |
| US-20090203673-A1 | 4-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| EP-1150963-A1 | SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Aventis Pharma Deutschland GmbH (DE) | 2001-11-07 | — | — | EP | disclosed |
| EP-0676429-B1 | Composition for urethane-based plastic lens | MITSUI CHEMICALS INC (JP) | 2000-12-27 | — | — | EP | disclosed |
| WO-2000046214-A1 | SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-08-10 | — | — | WO | disclosed |
| US-5693738-A | REACTING AN ISOCYANATE AND/OR AN ISOTHIOCYANATE COMPOUND WITH A HYDROXYL AND/OR MERCAPTO-CONTAINING COMPOUND IN THE PRESENCE OF A COMPLEX OF A TERTIARY AMINE AND A LEWIS ACID | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0676429-A2 | Composition for urethane-base plastic lens | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203673-A1 | 4-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | CCNI, MKI67, CCNA1 | ALDH1A1 293/4885TSHR 1848/4885POLB 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.