Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737353 | 0.88 | PTGER4 (0.57) | CHRNA4CTRCPTGER4ABCC4LMNA | |
| SCHEMBL7285067 | 0.84 | CHRNA4 (0.49) | CHRNA4CTRCPTGER4ABCC4LMNA | |
| SCHEMBL27679068 | 0.81 | CHRNA4 (0.50) | CHRNA4CTRCPTGER4ABCC4LMNA | |
| SCHEMBL27605092 | 0.80 | LMNA (0.42) | CHRNA4LMNAMAPT | |
| SCHEMBL27811533 | 0.80 | CHRNA4 (0.49) | CHRNA4PTGER4LMNAGAATSHR | |
| SCHEMBL13044154 | 0.80 | CHRNA4 (0.46) | CHRNA4CTRCPTGER4LMNAGAA | |
| SCHEMBL16691872 | 0.78 | RAB9A (0.56) | CHRNA4LMNATSHRALDH1A1HPGD | |
| SCHEMBL11795907 | 0.78 | PTGER4 (0.49) | CHRNA4PTGER4LMNATSHRALDH1A1 | |
| SCHEMBL27624018 | 0.78 | CYP2A6 (0.50) | ALDH1A1KMO | |
| SCHEMBL28878980 | 0.78 | CNR2 (0.55) | GAATSHRALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010056085-A1 | Methods of using vesicant drug formulations | RAMU AVNER (US) | 2001-12-27 | — | — | US | claimed |
| US-20010056085-A1 | Methods of using vesicant drug formulations | RAMU AVNER (US) | 2001-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056085-A1 | Methods of using vesicant drug formulations | UGT1A1, SLC47A1, UGT1A10 | CHRNA4 3718/4885CTRC 1292/4885PTGER4 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.