SCHEMBL7793412

SCHEMBL7793412

CCc1ccc(-c2ccc(C=NN=Cc3ccc(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.35
TRPA1 O75762 1/20 0.35
CHKA P35790 1/20 0.34
RARB P10826 1/20 0.34
NFE2L2 Q16236 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
MAPK1 P28482 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PKM P14618 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791154 0.92 MAOA (0.37) CHKARARBGRIN1GRIN2BNPC1
SCHEMBL7791283 0.92 CHKA (0.37) CHKARARBGRIN1GRIN2BNPC1
SCHEMBL7792141 0.90 RARB (0.38) PLA2G7TRPA1CHKARARBNFE2L2
SCHEMBL7789104 0.89 GCGR (0.38) CHKARARBGRIN1GRIN2BNPC1
SCHEMBL7793273 0.88 NPC1 (0.47) CHKARARBNFE2L2GRIN1GRIN2B
SCHEMBL7788188 0.86 RARB (0.41) CHKARARBGRIN1GRIN2BNPC1
SCHEMBL7792424 0.86 NPC1 (0.46) RARBNFE2L2GRIN1GRIN2BNPC1
SCHEMBL7789206 0.86 NPC1 (0.46) RARBNFE2L2GRIN1GRIN2BNPC1
SCHEMBL7793238 0.85 PLA2G7 (0.42) PLA2G7TRPA1NFE2L2GRIN1GRIN2B
SCHEMBL7793232 0.85 PLA2G7 (0.42) PLA2G7TRPA1NFE2L2GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed