Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793448 | 1.00 | TRPA1 (0.42) | TRPA1PLA2G7NFE2L2GRIN1GRIN2B | |
| SCHEMBL7791861 | 0.88 | TRPA1 (0.40) | TRPA1PLA2G7NFE2L2GRIN1GRIN2B | |
| SCHEMBL7791857 | 0.88 | TRPA1 (0.40) | TRPA1PLA2G7NFE2L2GRIN1GRIN2B | |
| SCHEMBL7788223 | 0.87 | MAOA (0.40) | GRIN1GRIN2BNPC1RAB9AMAPK1 | |
| SCHEMBL7788227 | 0.87 | MAOA (0.40) | GRIN1GRIN2BNPC1RAB9AMAPK1 | |
| SCHEMBL7793629 | 0.86 | MAOB (0.41) | TRPA1NFE2L2GRIN1GRIN2BNPC1 | |
| SCHEMBL7793625 | 0.86 | MAOB (0.41) | TRPA1NFE2L2GRIN1GRIN2BNPC1 | |
| SCHEMBL7788198 | 0.86 | GRIN2D (0.41) | TRPA1GRIN1GRIN2BNPC1RAB9A | |
| SCHEMBL7788203 | 0.86 | GRIN2D (0.41) | TRPA1GRIN1GRIN2BNPC1RAB9A | |
| SCHEMBL7792457 | 0.85 | GRIN1 (0.42) | TRPA1PLA2G7NFE2L2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |