SCHEMBL77935

SCHEMBL77935

Fc1[c]cc(F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28540079 0.76 TRPV4 (0.38)
SCHEMBL15352657 0.75
SCHEMBL3643779 0.75
SCHEMBL6554168 0.75
SCHEMBL15351818 0.75
SCHEMBL9819211 0.75
SCHEMBL14880521 0.73 CTSL (0.34)
SCHEMBL5716350 0.73
SCHEMBL1392381 0.71
SCHEMBL5917278 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150318-A1 PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS THE SCRIPPS RESEARCH INSTITUTE 2024-05-09 US claimed
CN-113845637-B Method for preparing high-voltage-resistant integrally-oriented covalent organic framework electrolyte membrane 西湖大学 2024-04-19 CN claimed
EP-4352040-A1 PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS The Scripps Research Institute (US) 2024-04-17 EP claimed
CN-117794896-A Protease inhibitors for the treatment of coronavirus infections 斯克里普斯研究学院 2024-03-29 CN claimed
CN-117747951-A Lithium battery 三星SDI株式会社 2024-03-22 CN claimed
US-20240082435-A1 Solid phase synthesis of glutamate-urea-lysine derived (GUL derived) prostate-specific membrane antigen (PSMA) targeting conjugates and their use as precursors for therapeutic and/or diagnostic agents TELIX PHARMACEUTICALS (INNOVATIONS) PTY LTD (AU) 2024-03-14 US claimed
CN-117355343-A Solid phase synthesis of conjugates of glutamate-urea-lysine derived (GUL derived) targeted Prostate Specific Membrane Antigen (PSMA) and their use as precursors for therapeutic and/or diagnostic agents 泰利斯制药(创新)有限公司 2024-01-05 CN claimed
EP-4297804-A1 SOLID PHASE SYNTHESIS OF GLUTAMATE-UREA-LYSINE DERIVED (GUL DERIVED) PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) TARGETING CONJUGATES AND THEIR USE AS PRECURSORS FOR THERAPEUTIC AND / OR DIAGNOSTIC AGENTS Telix Pharmaceuticals (Innovations) Pty Ltd (AU) 2024-01-03 EP claimed
CN-117327240-A Preparation method and application of poly-aromatic tetrafluorophenyl imidazole polymer and high-temperature proton exchange membrane thereof 中国科学院大连化学物理研究所 2024-01-02 CN claimed
CN-117327239-A Preparation method and application of ether-bond-free poly-aromatic tetrafluorophenyl phosphonated and sulfonated polymer and proton exchange membrane thereof 中国科学院大连化学物理研究所 2024-01-02 CN claimed
EP-0378026-A1 Fluor derivatives of 3-ethenyl-2,2-dimethyl cyclopropane-carboxylic acid, method for their preparation, their use as pesticides and compositions containing them ROUSSEL-UCLAF (FR) 1990-07-18 EP claimed
US-4885027-A PLANT GROWTH REGULATORS; NONPHYTOTOXIC; PRE- AND POST EMERGENCE CHEVRON RESEARCH COMPANY (US) 1989-12-05 US claimed
EP-0218615-B1 PROCESS FOR THE MANUFACTURE OF BENZOYL UREA SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-07-12 EP claimed
US-4831179-A HERBICIDES CHEVRON RESEARCH COMPANY (US) 1989-05-16 US claimed
EP-0306943-A2 Immunconjugates joined by thioether bonds having reduced toxicity and improved selectivity NEORX CORPORATION (US) 1989-03-15 EP claimed
EP-0059291-B1 ANTIHYPERTENSIVE AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1985-03-27 EP claimed
EP-0010879-B1 HALOGENATED ESTERS OF CYCLOPROPANE ACIDS, THEIR PREPARATION, COMPOSITIONS AND USE AS PESTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-27 EP claimed
EP-0059291-A1 Antihypertensive agents AMERICAN HOME PRODUCTS CORPORATION (US) 1982-09-08 EP claimed
US-4213995-A HYPOTENSIVE AGENTS BOEHRINGER INGELHEIM GMBH (DE) 1980-07-22 US claimed
EP-0010879-A1 Halogenated esters of cyclopropane acids, their preparation, compositions and use as pesticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-05-14 EP claimed