SCHEMBL7793559

SCHEMBL7793559

C=CCc1ccc(/C=N/N=C/c2cc(F)c(F)c(F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
CYP3A4 P08684 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
XDH P47989 1/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPT P10636 3/20 0.35
PPARG P37231 2/20 0.35
PPARD Q03181 2/20 0.35
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH2 P05091 1/20 0.35
GABRA1 P14867 1/20 0.35
AKR1B1 P15121 1/20 0.35
HPGD P15428 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793562 1.00 ALDH1A1 (0.36) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL7791142 0.87 PLA2G7 (0.37) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL7791145 0.87 PLA2G7 (0.37) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL8139528 0.84 CA12 (0.33) ALDH1A1CYP3A4SMN1; SMN2MAPTNPC1
SCHEMBL8139527 0.84 CA12 (0.33) ALDH1A1CYP3A4SMN1; SMN2MAPTNPC1
SCHEMBL7791828 0.84 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL7791826 0.84 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL7789204 0.83 GRIN2D (0.46) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL7789200 0.83 GRIN2D (0.46) ALDH1A1CYP3A4SMN1; SMN2XDHTP53
SCHEMBL7789187 0.82 GRIN2D (0.37) ALDH1A1CYP3A4SMN1; SMN2MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed