Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793676 | 0.78 | DGKA (0.45) | DGKADNM1CYP3A4TSHRATM | |
| SCHEMBL2196519 | 0.77 | DGKA (0.62) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL7792766 | 0.76 | DGKA (0.43) | DGKADNM1CYP3A4TSHRATM | |
| SCHEMBL16173927 | 0.76 | DGKA (0.53) | DGKADNM1TSHRATMPRSS1 | |
| SCHEMBL8095315 | 0.76 | DGKA (0.51) | DGKADNM1CYP3A4TSHRATM | |
| SCHEMBL6742895 | 0.73 | DGKA (0.64) | DGKADNM1CYP3A4TSHRATM | |
| SCHEMBL18429952 | 0.72 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL187111 | 0.72 | DGKA (0.59) | DGKADNM1CYP3A4TSHRATM | |
| SCHEMBL3918716 | 0.72 | DGKA (0.56) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL2193854 | 0.72 | DGKA (0.56) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |