SCHEMBL2196519

SCHEMBL2196519

CCCCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCC(CCCCCC)C(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.62
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
NAAA Q02083 1/20 0.53
DNM1 Q05193 1/20 0.53
HTR2C P28335 1/20 0.51
MAPT P10636 1/20 0.50
LMNA P02545 2/20 0.49
ALDH1A1 P00352 1/20 0.49
PAM P19021 2/20 0.49
PLA2G2A P14555 2/20 0.48
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517306 0.94 DGKA (0.56) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL3918716 0.94 DGKA (0.56) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL2193854 0.94 DGKA (0.56) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL3927345 0.89 DGKA (0.50) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL9637091 0.89 DGKA (0.65) DGKAPRSS1PRSS2PRSS3NAAA
Cetyl Palmitate SCHEMBL8815494 0.89 DGKA (0.65) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL8815475 0.89 DGKA (0.65) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL8359802 0.87 DGKA (0.62) DGKAPRSS1PRSS2PRSS3NAAA
Cetyl Palmitate SCHEMBL7134252 0.87 DGKA (0.62) DGKAPRSS1PRSS2PRSS3NAAA
SCHEMBL8820849 0.87 DGKA (0.62) DGKAPRSS1PRSS2PRSS3NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173099-A1 LIPOLYSIS COMPOSITION USING SURFACE-MODIFIED GAS-GENERATING NANOPARTICLES SUPERNOVA BIO CO., LTD. (KR) 2023-06-08 US disclosed
US-11518735-B2 Pseudoceramide compound with improved stability and composition comprising same AE KYUNG INDUSTRIAL CO., LTD. (KR) 2022-12-06 US disclosed
CN-115297880-A Topical composition comprising extract of crude drug comprising arillus longan for treating or improving skin ulcer, and its application (株)美迪合伙来音 2022-11-04 CN disclosed
CN-115297879-A Topical composition comprising arillus longan combined crude drug extract for regenerating skin and treating or improving skin wound, and its application (株)美迪合伙来音 2022-11-04 CN disclosed
CN-115279387-A Topical composition comprising arillus longan combined crude drug extract for inhibiting TSLP and treating or improving skin inflammation diseases, and its application (株)美迪合伙来音 2022-11-01 CN disclosed
US-20200354309-A1 NOVEL PSEUDOCERAMIDE COMPOUND WITH IMPROVED STABILITY AND COMPOSITION COMPRISING SAME AE KYUNG INDUSTRIAL CO., LTD (KR) 2020-11-12 US disclosed
US-10695314-B2 Antimicrobial composition containing 7,10-epoxyoctadeca-7,9-dienoic acid as active ingredient KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-06-30 US disclosed
US-20190133989-A1 ANTIMICROBIAL COMPOSITION CONTAINING 7,10-EPOXYOCTADECA-7,9-DIENOIC ACID AS ACTIVE INGREDIENT KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2019-05-09 US disclosed
US-10233143-B2 Pseudoceramide compound, and external use skin preparation composition containing same AE KYUNG INDUSTRIAL CO., LTD (KR) 2019-03-19 US disclosed
US-20170313648-A1 NOVEL PSEUDOCERAMIDE COMPOUND, AND EXTERNAL USE SKIN PREPARATION COMPOSITION CONTAINING SAME AE KYUNG INDUSTRIAL CO., LTD (KR) 2017-11-02 US disclosed
US-20090030100-A1 FINE PORE FORMATION AGENT FOR POROUS RESIN FILM AND COMPOSITION CONTAINING THE SAME FOR POROUS RESIN FILM MARUO CALCIUM CO., LTD. (JP) 2009-01-29 US disclosed
EP-1985650-A1 MICROPORE FORMING AGENT FOR POROUS RESIN FILM AND COMPOSITION FOR POROUS RESIN FILM CONTAINING THE AGENT MARUO CALCIUM COMPANY LIMITED (JP) 2008-10-29 EP disclosed
CN-101291679-A Compositions comprising actinidia and methods of use thereof EFFICAS INC PANGENOMICS CO LTD (US) 2008-10-22 CN disclosed
US-20080182933-A1 useful for a light reflector of, for example, a liquid crystal display and a lighting apparatus; diaphragm (separator) between electrodes of a battery MARUO CALCIUM COMPANY LIMITED (JP) 2008-07-31 US disclosed
CN-1960698-A Local slimming preparation and cosmetic containing carnitine derivative SHOWA DENKO KK (JP) 2007-05-09 CN disclosed
CN-1297266-C Stabilized ascorbic acid derivatives SHOWA DENKO KK (JP) 2007-01-31 CN disclosed
CN-1678333-A Composition containing extract of actinidia arguta and related species for preventing and treating allergic diseases and non-allergic inflammatory diseases PANGENOMICS CO LTD (KR) 2005-10-05 CN disclosed
CN-1658864-A Stabilized ascorbic acid derivatives SHOWA DENKO KK (JP) 2005-08-24 CN disclosed
CN-1197542-C Cosmetics KYOWA HAKKO KOGYO KK (JP) 2005-04-20 CN disclosed
CN-1328813-A Cosmetics KYOWA HAKKO KOGY CO LTD (JP) 2002-01-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11518735-B2 Pseudoceramide compound with improved stability and composition comprising same CERS2, ASAH2, ASAH1 DGKA 193/4885PRSS1 671/4885PRSS2 1912/4885
US-20200354309-A1 NOVEL PSEUDOCERAMIDE COMPOUND WITH IMPROVED STABILITY AND COMPOSITION COMPRISING SAME CERS2, ASAH2, CERT1 DGKA 214/4885PRSS1 544/4885PRSS2 1673/4885
US-10695314-B2 Antimicrobial composition containing 7,10-epoxyoctadeca-7,9-dienoic acid as active ingredient CYP51A1, IL17A, ELOVL5 DGKA 73/4885PRSS1 3084/4885PRSS2 3643/4885
US-20190133989-A1 ANTIMICROBIAL COMPOSITION CONTAINING 7,10-EPOXYOCTADECA-7,9-DIENOIC ACID AS ACTIVE INGREDIENT CYP51A1, IL17A, ELOVL5 DGKA 73/4885PRSS1 3084/4885PRSS2 3643/4885
US-20170313648-A1 NOVEL PSEUDOCERAMIDE COMPOUND, AND EXTERNAL USE SKIN PREPARATION COMPOSITION CONTAINING SAME CERS2, CERT1, ACER2 DGKA 453/4885PRSS1 320/4885PRSS2 594/4885
US-10233143-B2 Pseudoceramide compound, and external use skin preparation composition containing same CERS2, CERT1, ACER2 DGKA 572/4885PRSS1 395/4885PRSS2 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.