Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10430297 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL9629105 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL6055692 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL16166065 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL7793517 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| Hydrochloric Acid SCHEMBL9161840 | 0.98 | ALDH1A1 (0.61) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| Hydrochloric Acid SCHEMBL9166655 | 0.98 | ALDH1A1 (0.61) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL3319482 | 0.98 | ALDH1A1 (0.65) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL7540599 | 0.94 | ALDH1A1 (0.56) | ALDH1A1CYP3A4DRD2DRD3OPRM1 | |
| SCHEMBL1425130 | 0.93 | ALDH1A1 (0.69) | ALDH1A1CYP3A4DRD2DRD3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200466-A | Light-sensitive silver halide photographic materials | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-04-29 | — | — | US | claimed |
| EP-0900255-B1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SC HOLDING AG (CH) | 2001-12-19 | — | — | EP | disclosed |
| US-6156914-A | Donor-substituted oxindigo derivatives and their use as colorants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0900255-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | Ciba SC Holding AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041176-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-11-06 | — | — | WO | disclosed |
| US-4200466-A | Light-sensitive silver halide photographic materials | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-04-29 | — | — | US | disclosed |