Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542537 | 0.94 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL16166065 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL7793517 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL9629105 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL7793677 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL6055692 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL10430297 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9166655 | 0.92 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9161840 | 0.92 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HTR7DRD2DRD3 | |
| SCHEMBL3319482 | 0.92 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HTR7DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943661-B1 | Chromophoric compounds and their preparation process | SIEMENS AG (DE) | 2002-10-23 | — | — | EP | disclosed |
| EP-0943630-B1 | Nonlinear optically active copolymers, polymers materials prepared therefrom and electro-optical and photonic devices using the same | SIEMENS AG (DE) | 2002-06-05 | — | — | EP | disclosed |
| US-6353059-B2 | CROSSLINKING; STABLE MOLECULAR ORIENTATION | SIEMENS AKTIENGESELLSCHAFT (DE) | 2002-03-05 | — | — | US | disclosed |
| US-20010053818-A1 | Polyadducts produced from nonlinear-optically active copolymers and polymerizable nonlinear-optically active monomers | SIEMENS AKTIENGESELLSCHAFT | 2001-12-20 | — | — | US | disclosed |
| US-6284889-B1 | E.G, 9-(N-(N-HEPTYL)-N-(2-HYDROXYETHYL)AMINO)BENZO(D)ISOTHIAZOLO(3, 3A, 4-AB)PHEN-7,12-OXAZINE 4-DIOXIDE. | SIEMENS AKTIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |
| US-6228977-B1 | HEAT RESISTANT, MOLECULAR ORIENTATION-STABLE MATERIAL PREPARED FROM NONLINEAR OPTICALLY ACTIVE CHROMOGEN COVALENTLY BOUND TO A CROSSLINKABLE OLIGO- OR POLYCYANURATE AND CURED; ELECTRO-OPTICAL DEVICES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |
| US-6174961-B1 | OPTICAL POLYMERS | SIEMENS AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |
| US-6126867-A | Nonlinear-optically active copolymers, polymer materials produced from them, and electrooptical and photonic components constructed therefrom | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| EP-0981069-A1 | Nonlinear optically active copolymers | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-02-23 | — | — | EP | disclosed |
| EP-0943630-A1 | Nonlinear optically active copolymers, polymers materials prepared therefrom and electro-optical and photonic devices using the same | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-09-22 | — | — | EP | disclosed |
| EP-0943661-A2 | Chromophoric compounds and their preparation process | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-09-22 | — | — | EP | disclosed |
| EP-0941990-A2 | Process for the preparation of azamethines and azamethines obtained thereby | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-09-15 | — | — | EP | disclosed |
| EP-0942019-A2 | Non-linear optically active copolymers, polyadducts formed from it and their use in non-linear optical media | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053818-A1 | Polyadducts produced from nonlinear-optically active copolymers and polymerizable nonlinear-optically active monomers | PARG, PARN, ACMSD | ALDH1A1 1865/4885CYP3A4 2763/4885HTR7 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.