Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784887 | 0.86 | MAPT (0.50) | MAPTALDH1A1HPGDCYP2A6NPC1 | |
| SCHEMBL6633670 | 0.84 | MEN1 (0.44) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5748294 | 0.82 | LCK (0.46) | MAPTCES2CES1 | |
| SCHEMBL27570133 | 0.75 | PLAU (0.56) | — | |
| SCHEMBL29356637 | 0.72 | ALDH1A1 (0.71) | MAPTALDH1A1HPGDCYP2A6NPC1 | |
| SCHEMBL30678318 | 0.72 | ALDH1A1 (0.71) | MAPTALDH1A1HPGDCYP2A6NPC1 | |
| SCHEMBL43058 | 0.72 | ALDH1A1 (0.71) | MAPTALDH1A1HPGDCYP2A6NPC1 | |
| SCHEMBL834744 | 0.71 | CYP2A6 (0.68) | MAPTALDH1A1HPGDCYP2A6NPC1 | |
| SCHEMBL1553066 | 0.71 | ALDH1A1 (0.69) | MAPTALDH1A1HPGDCYP2A6NPC1 | |
| SCHEMBL1090982 | 0.71 | CYP1A2 (0.48) | ALDH1A1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155698-A1 | ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES | Nitto Kasei Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |