Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814341 | 1.00 | MGLL (0.41) | MGLLFAAHPIK3CDBRD4BRD2 | |
| SCHEMBL7059780 | 1.00 | MGLL (0.41) | MGLLFAAHPIK3CDBRD4BRD2 | |
| SCHEMBL7794085 | 0.95 | FAAH (0.46) | MGLLFAAHPIK3CDALOX5 | |
| SCHEMBL7794084 | 0.95 | FAAH (0.46) | MGLLFAAHPIK3CDALOX5 | |
| SCHEMBL7803803 | 0.93 | FAAH (0.45) | MGLLFAAHALOX5TSHR | |
| SCHEMBL18935700 | 0.93 | FAAH (0.45) | MGLLFAAHALOX5TSHR | |
| SCHEMBL18935701 | 0.93 | FAAH (0.45) | MGLLFAAHALOX5TSHR | |
| SCHEMBL7803804 | 0.93 | FAAH (0.45) | MGLLFAAHALOX5TSHR | |
| SCHEMBL5800684 | 0.93 | FAAH (0.39) | MGLLFAAHPIK3CD | |
| SCHEMBL7799654 | 0.89 | PIK3CD (0.39) | MGLLFAAHPIK3CDBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371238-A | Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0555483-B1 | PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE | HISAMITSU PHARMACEUTICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5371238-A | Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0555483-A1 | PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-3975534-A | Pharmaceutical compositions useful for treating tick infestation in animals which contain 2-aryliminopyrrolidines or their salts as the active agent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |