Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.45 |
| ▸ | RHOC | P08134 | 2/20 | 0.44 |
| ▸ | RHOA | P61586 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23961209 | 0.98 | ALDH1A1 (0.53) | ALDH1A1PRSS1KCNH3RHOCRHOA | |
| SCHEMBL909141 | 0.94 | L3MBTL1 (0.47) | ALDH1A1PRSS1RHOCRHOALMNA | |
| SCHEMBL2784124 | 0.89 | ALDH1A1 (0.64) | ALDH1A1PRSS1KCNH3F2PRSS2 | |
| SCHEMBL296404 | 0.85 | HPGD (0.46) | ALDH1A1RHOCRHOALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL27687293 | 0.83 | HPGD (0.45) | ALDH1A1KCNH3RHOCRHOALMNA | |
| SCHEMBL29722205 | 0.82 | ALDH1A1 (0.55) | ALDH1A1PRSS1KCNH3F2PRSS2 | |
| SCHEMBL10785116 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PRSS1KCNH3F2PRSS2 | |
| SCHEMBL13591304 | 0.81 | GCGR (0.46) | ALDH1A1 | |
| SCHEMBL9639726 | 0.79 | MAPT (0.55) | ALDH1A1RHOCRHOALMNAMEN1 | |
| SCHEMBL14972359 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PRSS1KCNH3F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102060713-A | Aromatic amine hapten for detecting azo dyes and preparation method thereof | JIAXING ENTRY EXIT INSPECTION AND QUARANTINE BUREAU OF P R C | 2011-05-18 | — | — | CN | disclosed |
| EP-1150963-A1 | SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Aventis Pharma Deutschland GmbH (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000046214-A1 | SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-08-10 | — | — | WO | disclosed |