Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415599 | 0.84 | PKM (0.59) | HRH1HTR2APKMCTDSP1MEN1 | |
| Hydrochloric Acid SCHEMBL9396254 | 0.83 | PKM (0.57) | HRH1HTR2APKMCTDSP1MEN1 | |
| SCHEMBL1734494 | 0.82 | MEN1 (0.51) | HTR2APKMCTDSP1MEN1KMT2A | |
| SCHEMBL11743901 | 0.81 | HTR2A (0.52) | HRH1HTR2APKMCTDSP1MEN1 | |
| SCHEMBL31265279 | 0.79 | PKM (0.53) | PKMCTDSP1MEN1KMT2AMITF | |
| SCHEMBL3907335 | 0.78 | MEN1 (0.55) | HRH1HTR2APKMCTDSP1MEN1 | |
| SCHEMBL7766277 | 0.77 | PKM (0.55) | PKMCTDSP1MEN1KMT2AMITF | |
| SCHEMBL2085660 | 0.77 | MEN1 (0.58) | HRH1HTR2APKMCTDSP1MEN1 | |
| SCHEMBL28516557 | 0.76 | PKM (0.61) | PKMCTDSP1MEN1KMT2AMITF | |
| SCHEMBL30982192 | 0.76 | KMT2A (0.57) | PKMCTDSP1MEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1355696-A | Method to aid smoking cessation | KNOLL PHARMACEUTICAL CO (US) | 2002-06-26 | — | — | CN | disclosed |
| EP-1150672-A1 | METHOD TO AID SMOKING CESSATION | KNOLL PHARMACEUTICAL COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-1150672-A1 | METHOD TO AID SMOKING CESSATION | KNOLL PHARMACEUTICAL COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000043002-A1 | METHOD TO AID SMOKING CESSATION | KNOLL PHARMACEUTICAL COMPANY (US) | 2000-07-27 | — | — | WO | disclosed |
| WO-2000043002-A1 | METHOD TO AID SMOKING CESSATION | KNOLL PHARMACEUTICAL COMPANY (US) | 2000-07-27 | — | — | WO | disclosed |