Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30982183 | 0.95 | KMT2A (0.63) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL5652288 | 0.83 | MEN1 (0.58) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL27661415 | 0.80 | PKM (0.57) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL8007179 | 0.79 | KMT2A (0.67) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL31265279 | 0.78 | PKM (0.53) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL30982177 | 0.77 | MEN1 (0.56) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL4180738 | 0.77 | FFAR1 (0.61) | KMT2AMEN1PKMFFAR1NR3C2 | |
| SCHEMBL7794187 | 0.76 | HRH1 (0.53) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL7194995 | 0.75 | PKM (0.56) | KMT2AMEN1PKMCTDSP1FFAR1 | |
| SCHEMBL6989805 | 0.75 | KMT2A (0.44) | KMT2AMEN1PKMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153595-A1 | CHROMANE DERIVATIVES AS EGFR SELECTIVE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-25 | — | — | WO | disclosed |