Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.70 |
| ▸ | RXRA | P19793 | 10/20 | 0.52 |
| ▸ | RARB | P10826 | 9/20 | 0.52 |
| ▸ | RXRB | P28702 | 9/20 | 0.52 |
| ▸ | RARG | P13631 | 8/20 | 0.52 |
| ▸ | RXRG | P48443 | 6/20 | 0.52 |
| ▸ | RARA | P10276 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794236 | 0.91 | CYP26A1 (0.70) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL6733878 | 0.89 | CYP3A4 (0.71) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL7802940 | 0.87 | CYP26A1 (0.53) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL7802063 | 0.86 | RXRA (0.54) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL7810742 | 0.84 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL5078193 | 0.83 | CYP26A1 (1.00) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL7799983 | 0.80 | RXRA (0.56) | CYP26A1CYP26B1RXRARARBRXRB | |
| SCHEMBL7803974 | 0.80 | CYP26A1 (0.55) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL6732613 | 0.80 | CYP3A4 (0.71) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL7771294 | 0.78 | RARG (0.57) | CYP26A1CYP3A4CYP26B1RXRARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030952-A | AS HUMAN AND VETERINARY MEDICINE, PARTICULARLY IN THE TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR AND OPHTHALMOLOGIC CONDITIONS, AND IN COSMETIC COMPOSITIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES GALDERMA (FR) | 2000-02-29 | — | — | US | disclosed |