Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 11/20 | 0.40 |
| ▸ | RARB | P10826 | 11/20 | 0.40 |
| ▸ | RARG | P13631 | 10/20 | 0.40 |
| ▸ | RXRA | P19793 | 6/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10438757 | 0.79 | RARB (0.42) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL448167 | 0.77 | TSHR (0.47) | RARARARBRARGRXRARXRB | |
| SCHEMBL3277951 | 0.76 | APP (0.44) | — | |
| SCHEMBL6321027 | 0.75 | ACHE (0.50) | — | |
| SCHEMBL9476182 | 0.74 | APP (0.50) | — | |
| SCHEMBL8072424 | 0.73 | POLB (0.39) | — | |
| SCHEMBL6373056 | 0.73 | TSHR (0.53) | — | |
| SCHEMBL5846459 | 0.73 | RARB (0.60) | RARARARBRARGRXRARXRB | |
| SCHEMBL11385468 | 0.72 | POLB (0.46) | — | |
| SCHEMBL10577172 | 0.72 | HSPB1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |
| EP-0952974-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999010308-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1999-03-04 | — | — | WO | disclosed |