Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 15/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 15/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 12/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 12/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794868 | 0.76 | FDFT1 (0.66) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL19796165 | 0.74 | KCNQ3 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL7784731 | 0.73 | FDFT1 (0.50) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL7662714 | 0.73 | RRM2 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL17604124 | 0.73 | KCNQ3 (0.46) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL4442545 | 0.72 | ADRA2A (0.49) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL19796124 | 0.71 | MAPT (0.46) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL25191294 | 0.71 | KCNQ3 (0.50) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL7784733 | 0.70 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL7794284 | 0.70 | KCNQ3 (0.45) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077792-C | Pyridyl bisphosphonates for use as therapeutic agents | LEIRAS OY (FI) | 2002-01-16 | — | — | CN | disclosed |
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | disclosed |
| US-6083938-A | TREATING BONE DISEASES SELECTED FROM THE GROUP CONSISTING OF OSTEOLYTIC BONE DISEASES DUE TO MALIGNANCY, PAGET'S DISEASE AND PRIMARY AND SECONDARY OSTEOPOROSIS | LEIRAS OY (FI) | 2000-07-04 | — | — | US | disclosed |
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |
| CN-1149830-A | Pyridylbisphosphonates for use as therapeutical agent | LEIRAS OY (FI) | 1997-05-14 | — | — | CN | disclosed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | disclosed |