Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801986 | 0.84 | DRD2 (0.50) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL7803132 | 0.82 | PDE3B (0.49) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL7802210 | 0.81 | KDM4E (0.52) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL6031875 | 0.79 | PDE3B (0.53) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL7854620 | 0.79 | CA12 (0.54) | ALDH1A1KDM4EMEN1PDE5ACYP1A2 | |
| SCHEMBL7802069 | 0.79 | KDM4E (0.50) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL6585256 | 0.77 | PDE3B (0.53) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL8860906 | 0.76 | DRD2 (0.59) | DRD2KDM4EFAAH | |
| SCHEMBL5474312 | 0.76 | PDE3B (0.55) | DRD2ALDH1A1KDM4EMEN1PDE5A | |
| SCHEMBL8860585 | 0.76 | PDE3B (0.52) | DRD2ALDH1A1KDM4EMEN1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796248-B1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | WESTERN THERAPEUTICS INST D (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6143763-A | Carbostyril derivatives | D. WESTERN THERAPEUTICS INSTITIUTE (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0796248-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997012869-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-10 | — | — | WO | disclosed |