Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701156 | 0.82 | PPARG (0.83) | DRD2PPARGKDM4EMAPK1BCHE | |
| SCHEMBL7801986 | 0.79 | DRD2 (0.50) | DRD2KDM4EFAAH | |
| SCHEMBL3373971 | 0.79 | MAOB (0.65) | PPARGKDM4EMAOAACHEMAOB | |
| SCHEMBL5701304 | 0.78 | PPARG (0.91) | DRD2PPARGKDM4EMAPK1BCHE | |
| SCHEMBL7803132 | 0.78 | PDE3B (0.49) | DRD2KDM4EFAAH | |
| SCHEMBL9319380 | 0.78 | PPARG (0.74) | DRD2PPARGKDM4EMAPK1BCHE | |
| Chlorobenzene SCHEMBL11276027 | 0.78 | F11 (0.47) | DRD2KDM4EFAAH | |
| SCHEMBL20029447 | 0.77 | DRD2 (0.65) | DRD2 | |
| SCHEMBL11268673 | 0.77 | KDM4E (0.46) | DRD2KDM4EACHEMAOBFAAH | |
| SCHEMBL8860585 | 0.77 | PDE3B (0.52) | DRD2KDM4EFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658926-A | ANTICOAGULANTS, ANTIHISTAMINES, ANTIARRHYTHMIC, CARTIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |