⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969594 | 0.82 | CHRNA4 (0.47) | — | |
| SCHEMBL263448 | 0.80 | — | — | |
| SCHEMBL10085693 | 0.80 | — | — | |
| SCHEMBL426232 | 0.78 | — | — | |
| SCHEMBL20743009 | 0.78 | CHRNA4 (0.45) | — | |
| SCHEMBL28164185 | 0.78 | CHRNA4 (0.45) | — | |
| SCHEMBL1932936 | 0.78 | — | — | |
| SCHEMBL6341220 | 0.78 | P2RX7 (0.47) | — | |
| SCHEMBL27987440 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL13181076 | 0.75 | CHRNA4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104356127-B | Containing the double heterocyclic amides of N and its application as immunodepressant | 重庆理工大学 | 2017-06-16 | — | — | CN | disclosed |
| EP-2643323-B1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENT MANAGEMENT (AU) | 2015-10-14 | — | — | EP | disclosed |
| US-8796303-B2 | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-08-05 | — | — | US | disclosed |
| US-8796303-B2 | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-08-05 | — | — | US | disclosed |
| CN-102875569-A | Isoxazole pyrimidone (or triazone) compounds with herbicidal activity and anti-liver cancer activity | UNIV NANKAI | 2013-01-16 | — | — | CN | disclosed |
| US-20120135998-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD | 2012-05-31 | — | — | US | disclosed |
| US-20120135998-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD | 2012-05-31 | — | — | US | disclosed |
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | PAMUKCU RIFAT (US) | 2001-10-18 | — | — | US | disclosed |
| US-6262059-B1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | CELL PATHWAYS, INC. | 2001-07-17 | — | — | US | disclosed |
| US-5075488-A | Fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0128006-B1 | A SOIL-DISEASE-CONTROLLING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4709052-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4001237-A | HYPOTENSIVES | BRISTOL-MYERS COMPANY (US) | 1977-01-04 | — | — | US | disclosed |