Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.54 |
| ▸ | XIAP | P98170 | 4/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 6/20 | 0.36 |
| ▸ | F3 | P13726 | 6/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785888 | 0.94 | GHSR (0.53) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7786886 | 0.94 | GHSR (0.55) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL8331519 | 0.93 | GHSR (0.57) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7792151 | 0.93 | GHSR (0.55) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7785953 | 0.92 | GHSR (0.47) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7791668 | 0.91 | GHSR (0.55) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7785874 | 0.91 | GHSR (0.60) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7794384 | 0.91 | GHSR (0.67) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7786077 | 0.90 | GHSR (0.53) | GHSRXIAPAGTR1DRD2DRD4 | |
| SCHEMBL7791686 | 0.90 | GHSR (0.53) | GHSRXIAPAGTR1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |