SCHEMBL7794499

SCHEMBL7794499

CCC(F)C(Cl)CCCCCl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15380636 0.83 TSHR (0.42) TSHRALDH1A1TDP1
SCHEMBL23280314 0.75
SCHEMBL28332622 0.73 ALDH1A1 (0.33) TSHRALDH1A1TDP1
SCHEMBL1961201 0.73 ALDH1A1 (0.33) TSHRALDH1A1TDP1
SCHEMBL10659581 0.73 TSHR (0.35) TSHRALDH1A1TDP1
SCHEMBL9344838 0.72 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL26257923 0.71 TSHR (0.39) TSHRALDH1A1TDP1
SCHEMBL6577894 0.70 TSHR (0.35) TSHRALDH1A1TDP1
SCHEMBL4443603 0.70
SCHEMBL10593470 0.70 ALDH1A1 (0.31) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001208736-A METHOD OF MEASURING MOLECULAR WEIGHT OF FLUORINE-BASED ORGANIC COMPOUND ASAHI GLASS CO LTD 2001-08-03 JP disclosed