SCHEMBL9344838

SCHEMBL9344838

ClCCCCCCC(Cl)C(Cl)CCCCCCl

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29109626 0.97 ALDH1A1 (0.38) TSHRALDH1A1TDP1
SCHEMBL686673 0.88 ALDH1A1 (0.36) TSHRALDH1A1TDP1
SCHEMBL28832888 0.88 ALDH1A1 (0.36) TSHRALDH1A1TDP1
SCHEMBL10395460 0.88 ALDH1A1 (0.36) TSHRALDH1A1TDP1
SCHEMBL2230951 0.87 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL18109776 0.87 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL616561 0.87 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL8820342 0.87 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL8819608 0.87 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL8820672 0.87 ALDH1A1 (0.32) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5306805-A From dihalogenated aromatic compounds and alkali metal sulfides BAYER AG (DE) 1994-04-26 US disclosed
EP-0501217-A2 Process for preparing polyarylene sulphides BAYER AG (DE) 1992-09-02 EP disclosed