Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5787898 | 0.84 | CRHR1 (0.47) | CRHR1GAA | |
| SCHEMBL5787607 | 0.74 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL5789972 | 0.74 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5787451 | 0.72 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL5787170 | 0.71 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL5790387 | 0.71 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5788526 | 0.69 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5787496 | 0.69 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5791266 | 0.68 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7803320 | 0.68 | ALDH1A1 (0.36) | CRHR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007867-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | CHEN YUHPYNG L (US) | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007867-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | CYP2D6, CYP2B6, CYP3A5 | CRHR1 2026/4885NPC1 762/4885GAA 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.