SCHEMBL7794555

SCHEMBL7794555

COCCN(CCOC)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.44
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.37
ACHE P22303 2/20 0.36
CRHR1 P34998 2/20 0.36
HPGD P15428 2/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18562084 0.91 KMT2A (0.37) LMNAALDH1A1TSHRHPGDHTT
SCHEMBL14620931 0.90 CRHR1 (0.42) CYP2C19LMNASMN1; SMN2ALDH1A1TSHR
SCHEMBL20207410 0.84 ALDH1A1 (0.37) ALDH1A1TSHRCRHR1HPGDTDP1
SCHEMBL18556272 0.81 MAPT (0.44) LMNASMN1; SMN2ALDH1A1TSHRCRHR1
SCHEMBL3956323 0.81 MEN1 (0.33) ALDH1A1TSHRCRHR1TDP1
SCHEMBL22082130 0.81 APP (0.37) ALDH1A1TSHRTDP1
SCHEMBL10485681 0.81 USP8 (0.37) LMNASMN1; SMN2ALDH1A1TSHRCRHR1
SCHEMBL10216056 0.81 ALDH1A1 (0.44) LMNASMN1; SMN2ALDH1A1TSHRTRPM8
SCHEMBL994614 0.81 TDP1 (0.54) CYP2C19ALDH1A1TSHRTDP1CYP1A2
SCHEMBL15008757 0.81 MEN1 (0.33) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125712-A1 SELF-LUMINOUS DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
EP-1511754-B1 MULTIMER FORMS OF MONO- AND BIS-ACYLPHOSPHINE OXIDES CIBA HOLDING INC (CH) 2008-07-23 EP disclosed
US-7196228-B2 Multimer forms of mono-and bis-acylphosphine oxides CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-27 US disclosed
US-7196228-B2 Multimer forms of mono-and bis-acylphosphine oxides CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-27 US disclosed
EP-1150963-A1 SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Aventis Pharma Deutschland GmbH (DE) 2001-11-07 EP disclosed
WO-2000046214-A1 SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-08-10 WO disclosed