Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794756 | 0.90 | ALDH1A1 (0.44) | MAPTALDH1A1KCNJ1LMNAPLA2G1B | |
| SCHEMBL27447055 | 0.80 | ALDH1A1 (0.63) | MAPTALDH1A1KCNJ1LMNAPLA2G1B | |
| SCHEMBL7794740 | 0.80 | HRH4 (0.52) | MAPTALDH1A1TDP1POLBKMT2A | |
| SCHEMBL7792323 | 0.80 | PIN1 (0.61) | MAPTALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL3640534 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1KCNJ1LMNAPLA2G1B | |
| SCHEMBL3935171 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1KCNJ1LMNAPLA2G1B | |
| Hydrochloric Acid SCHEMBL7794721 | 0.79 | HRH4 (0.51) | MAPTALDH1A1PKMTDP1KMT2A | |
| SCHEMBL7792099 | 0.78 | CHEK2 (0.45) | ALDH1A1PKMPOLBKMT2AKDM4E | |
| SCHEMBL7796362 | 0.77 | EGLN1 (0.57) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7796289 | 0.77 | PIN1 (0.64) | MAPTALDH1A1PKMPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |