SCHEMBL7794822

SCHEMBL7794822

CCCCCCCCCCOc1cnc(-c2ccc(Br)cc2)nc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.56
NPC1 O15118 6/20 0.56
KDM4E B2RXH2 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
HSD17B10 Q99714 2/20 0.56
MAPT P10636 3/20 0.50
RARB P10826 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 3/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
HTT P42858 1/20 0.45
NFKB1 P19838 2/20 0.44
NFKB2 Q00653 2/20 0.44
RELA Q04206 2/20 0.44
NR5A1 Q13285 1/20 0.44
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8035575 1.00 RAB9A (0.56) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL7856810 1.00 RAB9A (0.56) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL5866494 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL13987904 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL6017545 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9318472 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL5866522 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9239737 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9235626 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL6017464 0.89 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4066576-A None JP disclosed
EP-0435632-B1 Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions SUMITOMO CHEMICAL CO (JP) 2001-11-28 EP disclosed
EP-1067122-A2 Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-10 EP disclosed
EP-0643119-B1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL CO (JP) 2000-04-26 EP disclosed
US-6030546-A FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-29 US disclosed
EP-0628530-B1 ACETYLENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT, AND LIQUID CRYSTAL ELEMENT MADE THEREFROM SUMITOMO CHEMICAL CO (JP) 1999-03-24 EP disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
EP-0644249-B1 Optically inactive, mesomorphic compound, liquid crystal composition containing the compound, liquid crystal device using the compositon, liquid crystal apparatus and display method CANON KK (JP) 1998-12-09 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
US-5723610-A Alcohol reactants for forming phenylpyrimidine derivatives and process for preparing said alcohols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-03 US disclosed
US-5539115-A FERROELECTRIC CRYSTALS FOR OPTICAL APPARATUS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-23 US disclosed
US-5534188-A Acetylene derivatives, process for producing the same, liquid crystal composition containing the same as an active ingredient, and liquid crystal element using said liquid crystal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-09 US disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed
EP-0644249-A1 Optically inactive, mesomorphic compound, liquid crystal composition containing the compound, liquid crystal device using the compositon, liquid crystal apparatus and display method CANON KABUSHIKI KAISHA (JP) 1995-03-22 EP disclosed
EP-0643119-A1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-15 EP disclosed
US-5385692-A Improved response CANON KABUSHIKI KAISHA (JP) 1995-01-31 US disclosed
EP-0628530-A1 ACETYLENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT, AND LIQUID CRYSTAL ELEMENT MADE THEREFROM SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-12-14 EP disclosed
EP-0546338-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-06-16 EP disclosed
JP-H0466576-A PRODUCTION OF OPTICALLY ACTIVE PHENYLPYRIMIDINE DERIVATIVE SUMITOMO CHEM CO LTD 1992-03-02 JP disclosed
EP-0435632-A2 Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed