Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612952 | 0.89 | KDM4E (0.49) | HSD17B14KDM4ELMNAHSD17B10ESR1 | |
| SCHEMBL1951514 | 0.83 | FEN1 (0.52) | HSD17B14KDM4ELMNAHSD17B10ESR1 | |
| SCHEMBL857363 | 0.81 | ESR1 (0.68) | KDM4ELMNAHSD17B10ESR1ESR2 | |
| SCHEMBL30635318 | 0.81 | ESR1 (0.68) | KDM4ELMNAHSD17B10ESR1ESR2 | |
| SCHEMBL7794959 | 0.81 | HSD17B14 (0.51) | HSD17B14KDM4ELMNAHSD17B10HSD17B1 | |
| SCHEMBL7791042 | 0.81 | ERN1 (0.52) | HSD17B14KDM4ELMNAHSD17B10HSD17B1 | |
| SCHEMBL6249403 | 0.79 | MGLL (0.46) | ESR1MGLL | |
| SCHEMBL9740614 | 0.78 | MAPT (0.54) | KDM4ELMNAHSD17B10ESR1MEN1 | |
| SCHEMBL6249433 | 0.78 | MAPT (0.54) | KDM4ELMNAHSD17B10ESR1MEN1 | |
| SCHEMBL6250464 | 0.78 | MAPT (0.54) | KDM4ELMNAHSD17B10ESR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821050-B1 | Optically active compound and antiferroelectric liquid crystal composition containing the same | SEMICONDUCTOR ENERGY LAB (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5820782-A | LOW THRESHOLD VOLTAGE AND LOW VISCOSITY; PYRIMIDINE-BASED COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-10-13 | — | — | US | disclosed |
| EP-0821050-A1 | Optically active compound and antiferroelectric liquid crystal composition containing the same | Takasago International Corporation (JP) | 1998-01-28 | — | — | EP | disclosed |