Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560443 | 0.92 | MAPT (0.50) | MAPTKDM4EHTTGAAMEN1 | |
| SCHEMBL7803116 | 0.84 | KMT2A (0.46) | MAPTKDM4EKMT2ALMNA | |
| SCHEMBL6560818 | 0.82 | PDGFRB (0.49) | MAPTKDM4EMEN1KMT2APDGFRB | |
| SCHEMBL6562602 | 0.77 | PHGDH (0.57) | MAPTHTTGAAMEN1POLB | |
| SCHEMBL6559651 | 0.76 | L3MBTL1 (0.40) | MAPTKDM4EHTTGAAMEN1 | |
| SCHEMBL6559655 | 0.76 | MAPT (0.61) | MAPTKDM4EHTTGAAMEN1 | |
| SCHEMBL6561321 | 0.75 | KMT2A (0.52) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6562659 | 0.74 | PHGDH (0.54) | MEN1POLBKMT2A | |
| SCHEMBL6560454 | 0.73 | PHGDH (0.46) | MAPTKDM4EGAAMEN1POLB | |
| SCHEMBL6559635 | 0.73 | ALDH1A1 (0.61) | MAPTKDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075469-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-02-14 | — | — | EP | disclosed |
| WO-2000052001-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-09-08 | — | — | WO | disclosed |