Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974118 | 0.74 | — | — | |
| SCHEMBL11556904 | 0.71 | MAOA (0.49) | NOTUMMTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL7790791 | 0.64 | — | — | |
| SCHEMBL22635768 | 0.64 | CYP11B1 (0.37) | — | |
| SCHEMBL17241706 | 0.63 | — | — | |
| SCHEMBL7795107 | 0.62 | NOTUM (0.32) | NOTUMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8104862 | 0.61 | CYP1A2 (0.31) | — | |
| SCHEMBL9058873 | 0.60 | MAOA (0.41) | NOTUMMTNR1ANPC1RAB9AKDM4E | |
| SCHEMBL15009454 | 0.59 | NOTUM (0.57) | NOTUMALDH1A1 | |
| SCHEMBL709851 | 0.58 | TRPA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155698-A1 | ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES | Nitto Kasei Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |