SCHEMBL7795159

SCHEMBL7795159

COc1ccc(-c2nc(=O)c3ccc(OC)cc3o2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.58
ALDH1A1 P00352 8/20 0.53
KDM4E B2RXH2 7/20 0.53
MAPT P10636 7/20 0.53
HPGD P15428 5/20 0.53
HSD17B10 Q99714 5/20 0.53
CYP3A4 P08684 5/20 0.53
TP53 P04637 4/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
NPC1 O15118 6/20 0.52
RAB9A P51151 6/20 0.52
MAOA P21397 1/20 0.52
CA12 O43570 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228489 0.92 CA1 (0.57) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL12228491 0.92 CYP19A1 (0.60) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL12228484 0.88 MAPT (0.55) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL12228487 0.88 MAOB (0.54) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL9609212 0.87 MAPT (0.57) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL4023015 0.87 ALDH1A1 (0.63) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL13000992 0.80 ALDH1A1 (0.47) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL6469873 0.79 NPC1 (0.52) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL17254744 0.78 ALDH1A1 (0.48) MAOBALDH1A1KDM4EMAPTHPGD
SCHEMBL9616651 0.77 HPGD (0.66) ALDH1A1KDM4EMAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654469-B1 Stabilised polymers containing o-hydroxyphenyl-s-triazines CIBA SC HOLDING AG (CH) 2001-08-22 EP disclosed
US-5760111-A TEXTILE STABILIZERS WITH PHOTOSTABILIZERS, OXIDATION OR HEAT RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-02 US disclosed
US-5688995-A SUNSCREEN AGENTS CIBA-GEIGY CORPORATION (US) 1997-11-18 US disclosed
US-5591850-A STABILIZERS FOR TEXTILE FIBERS, COSMETIC SUNSCREENS CIBA-GEIGY CORPORATION (US) 1997-01-07 US disclosed
EP-0743309-A1 o-Hydroxyphenyl-s-triazines as UV stabilisers CIBA-GEIGY AG (CH) 1996-11-20 EP disclosed
EP-0654469-A1 O-Hydroxyphenyl-s-triazines as stabilisers for polymers CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed