SCHEMBL9609212

SCHEMBL9609212

COC(=O)c1ccc(-c2nc(=O)c3ccc(OC)cc3o2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.57
KDM4E B2RXH2 6/20 0.57
ALDH1A1 P00352 5/20 0.57
HPGD P15428 5/20 0.57
HSD17B10 Q99714 5/20 0.57
RAB9A P51151 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
NPC1 O15118 2/20 0.57
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
ATM Q13315 1/20 0.54
TP53 P04637 4/20 0.53
HDAC6 Q9UBN7 2/20 0.51
THRB P10828 2/20 0.49
TNKS O95271 1/20 0.49
ESR1 P03372 1/20 0.47
THRA P10827 1/20 0.47
VDR P11473 1/20 0.47
RXRA P19793 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609338 0.91 MAPT (0.57) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL7795159 0.87 MAOB (0.58) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL9608557 0.87 MAPT (0.72) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL9608566 0.84 MAPT (0.65) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL9608554 0.84 MAPT (0.71) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL9609310 0.83 MAPT (0.54) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12228489 0.83 CA1 (0.57) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12228491 0.82 CYP19A1 (0.60) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL9608562 0.80 RAB9A (0.68) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12228487 0.80 MAOB (0.54) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077330-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885KDM4E 543/4885ALDH1A1 847/4885
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION AVPR1B, H1-0, H1-2 MAPT 2637/4885KDM4E 1403/4885ALDH1A1 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.