Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7029028 | 0.90 | POLB (0.55) | POLBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11818282 | 0.81 | GAA (0.57) | POLBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL7536579 | 0.79 | HTR1A (0.56) | POLBTSHRALDH1A1MAPTHTR1A | |
| SCHEMBL6930570 | 0.78 | POLB (0.64) | POLBALDH1A1MAPTLMNAHTR1A | |
| SCHEMBL6930821 | 0.76 | MAPT (0.48) | POLBALDH1A1MAPTLMNAHTR1A | |
| SCHEMBL9991858 | 0.73 | HTR1A (0.61) | POLBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11509122 | 0.73 | GAA (0.61) | POLBTSHRALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9993325 | 0.72 | HTR1A (0.60) | POLBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL7671076 | 0.72 | DRD2 (0.63) | POLBALDH1A1MAPTLMNAHTR1A | |
| Hydrochloric Acid SCHEMBL11817434 | 0.72 | GAA (0.60) | POLBTSHRALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |